Association of human cytomegalovirus viremia with human leukocyte antigens in liver transplantation recipients

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Association of human cytomegalovirus viremia with human leukocyte antigens in liver transplantation recipients.

Human cytomegalovirus (HCMV) reactivation is a common complication after liver transplantation (LT). Here, we investigated whether human leukocyte antigen (HLA)-matching was related to HCMV infection and subsequent graft failure after LT for hepatitis B virus  cirrhosis. This retrospective study reviewed 91 LT recipients. All the patients were grouped according to HLA-A, HLA-B, and HLA-DR locus...

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Association of Human Leukocyte Antigens Class I & II with Graves’ Disease in Iranian Population

Background: Graves’ disease (GD), a highly rampant autoimmune disorder of the thyroid gland, is responsible for 60-80% of the clinical cases of hyperthyroidism. Over the past decades, genetic association studies have identified several GD susceptibility loci in CTLA-4, TSHR and major histocompatibility complex regions. The information on the association between the human leukocyte antigens (HLA...

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Effects of donor/recipient human leukocyte antigen mismatch on human cytomegalovirus replication following liver transplantation

BACKGROUND Natural immunity against cytomegalovirus (CMV) can control virus replication after solid organ transplantation; however, it is not known which components of the adaptive immune system mediate this protection. We investigated whether this protection requires human leukocyte antigen (HLA) matching between donor and recipient by exploiting the fact that, unlike transplantation of other ...

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human leukocyte antigen alleles and cytomegalovirus infection after renal transplantation

results of all participants, 104 patients (52%) were diagnosed with cmv infection. there was no significant difference between the two groups, with and without cmv infection, in terms of patient’s characteristics. the cmv infection, in patients receiving a transplanted organ from deceased donor, was significantly more prevalent than in those receiving kidney transplant from living donor (63% vs...

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Meningioma: is there an association with human leukocyte antigens?

The expression of human leukocyte antigen (HLA) alleles plays an important role in the development and recurrence of benign and malignant diseases. Association of single HLA alleles or haplotypes with neoplastic processes has been investigated previously, and correlation between HLA and solid tumors, such as head and neck cancers or uterine cervical squamous epithelial lesions, were reported. H...

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ژورنال

عنوان ژورنال: Acta Biochimica et Biophysica Sinica

سال: 2011

ISSN: 1672-9145,1745-7270

DOI: 10.1093/abbs/gmr043